Health / Medical
11:10:35 AM 07.10.09
The JUPITER trial
Late in November, the results from the JUPITER trial got so much hype that it seemed scientists had found an actual magic "cholesterol pill."
Drugmaker AstraZeneca sponsored the huge 18,000-participant JUPITER trial of Crestor, its cholesterol-lowering drug (called a statin).
The trial was supposed to last five years, but the drug company cut it short after two years claiming Crestor was so effective that it was unethical to withhold the drug from those on placebo.
According to the results, Crestor reduced heart attack, stroke and hospitalization and other markers for heart troubles by 56 percent. The authors of the study concluded that the drug was so effective that it should even be given to people whose cholesterol was normal but had high C-reactive protein levels, a signs of inflammation in the body.
Not all doctors were as sold on the results. Many said exercise and diet changes were more effective than drugs, and obviously do not carry any side effects. Some questioned whether the numbers really supported such a high effectiveness.
However, the news still had many doctors excited. According to the results from a New England Journal of Medicine Web site poll, 48 percent of the 2,500 responders felt statin drugs should be used differently after the JUPITER trial.
http://abcnews.go.com/Health/YearInReview/story?id=6512364&page=1
Drugmaker AstraZeneca sponsored the huge 18,000-participant JUPITER trial of Crestor, its cholesterol-lowering drug (called a statin).
The trial was supposed to last five years, but the drug company cut it short after two years claiming Crestor was so effective that it was unethical to withhold the drug from those on placebo.
According to the results, Crestor reduced heart attack, stroke and hospitalization and other markers for heart troubles by 56 percent. The authors of the study concluded that the drug was so effective that it should even be given to people whose cholesterol was normal but had high C-reactive protein levels, a signs of inflammation in the body.
Not all doctors were as sold on the results. Many said exercise and diet changes were more effective than drugs, and obviously do not carry any side effects. Some questioned whether the numbers really supported such a high effectiveness.
However, the news still had many doctors excited. According to the results from a New England Journal of Medicine Web site poll, 48 percent of the 2,500 responders felt statin drugs should be used differently after the JUPITER trial.
http://abcnews.go.com/Health/YearInReview/story?id=6512364&page=1
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